中国当代儿科杂志2011,Vol.13Issue(9):722-724,3.
血清铁蛋白与儿童注意缺陷多动障碍关系的Meta分析
Relationship between serum ferritin levels and susceptibility to attention deficit hyperactivity disorder in children:a Meta analysis
谭利娜 1卫海燕 1张耀东 1卢爱莲 2李颖2
作者信息
- 1. 郑州市儿童医院,河南,郑州,450053
- 2. 新乡医学院第二附属医院临床心身二科,河南,新乡,453002
- 折叠
摘要
Abstract
Objective To study the possible relationship between serum ferritin levels and susceptibility to attention deficit hyperactivity disorder ( ADHD) in children. Methods Trie papers relating to the relationship between serum ferritin levels and susceptibility to childhood ADHD were searched in the Database CBM, CNKI, VIP and PubMed. The Meta-analysis software RevMan S.O was used for the heterogeneity test and for the pooled OR calculation. Sensitivity and publication bias analysis were performed. Results Five control studies were included for the Meta analysis, including 2S8 cases of ADHD and 138 control cases. There was heterogeneity in the studies on the relationship between serum ferritin levels and susceptibility to childhood ADHD ( P = 0. 003 ). So the studies were analyzed using the random-effect model. The pooled OR of serum ferritin levels and susceptibility to childhood ADHD was - 23. 09 ( 95% C/: - 33. 06 - 13.13; P <0.00001). The funnel plots did not indicate the existence of publication bias. Conclusions The results from present Meta analysis can prove that serum ferritin levels are associated with susceptibility to childhood ADHD.关键词
铁蛋白/注意缺陷多动障碍/Meta分析/儿童Key words
Ferritin/ Attention deficit hyperactivity disorder/ Meta analysis/ Child分类
医药卫生引用本文复制引用
谭利娜,卫海燕,张耀东,卢爱莲,李颖..血清铁蛋白与儿童注意缺陷多动障碍关系的Meta分析[J].中国当代儿科杂志,2011,13(9):722-724,3.