中药材2011，Vol.33Issue(7)：1055-1057,3.
山核桃外蒲壳化学成分及抗肿瘤活性研究
Chemical Constituents of Carya cathayensis and Their Antitumor Bioactivity
摘要
Abstract
Objective: To investigate the chemical constituents of Carya cathayensis and their antitumor bioactivity. Methods: The compounds were isolated by Sephadex LH-20 and silica gel column chromatography. Their structures were identified by physicochemical properties and spectroscopic analysis. Then their cytotoxic activity was studied. Results: Five compounds were elucidated as chry-sophanol( 1) ,physcion(2) ,β-sitosterol(3) ,pinostrobin(4) ,4,8-dihydroxy-1-tetralone(5). Conclusion; Compounds 2 and 3 are isolated from Carya cathayensis for the first time. In the MTT antitumor experiments, the compounds 1,4 and 5 have the cytotoxic activity to KB cell.关键词
山核桃外蒲壳/化学成分/抗肿瘤活性/人肝癌细胞Key words
Carya cathayensis Sarg/Chemical constituents/ Cytotoxic activity/HepG2分类
医药卫生引用本文复制引用
吴德玲,陈仕云,刘劲松,金传山,许凤清..山核桃外蒲壳化学成分及抗肿瘤活性研究[J].中药材,2011,33(7):1055-1057,3.基金项目
安徽中医学院合作研究项目(2008HZ001) （2008HZ001）
