组织工程与重建外科杂志2011，Vol.7Issue(4)：231-234,4.DOI:10.3969/j.issn.1673-0364.2011.04.014
人脂肪干细胞在骨组织工程中应用的研究进展
The Application of Human Adipose-Derived Stem Cells in Bone Tissue Engineering
摘要
Abstract
The reconstruction of large bone defects has been an important issue in clinical practice. Recently, bone tissue engineering combining with stem cell has emerged as one of the most promising therapeutic modality for clinical use. Human adipose-derived stem cell (hADSC) have now considered to be a promising stem cell source in bone tissue engineering, mainly due to its wide availability, easy access and the ability of osteogenesis both in vitro and vivo. This review aims to characterize human ADSC based on its surface proteins, the osteogenesis in vivo, the molecular mechanism of regulating osteogenesis and the effect of bone morphogenetic protein-2 (BMP2) on the osteogenic capacity of human ADSC.关键词
人脂肪干细胞/骨组织工程/成骨分化调控/骨形态发生蛋白2Key words
Human adipose-derived stem cells/Bone tissue engineering/Regulation of osteogenesis/Bone morphogenetic protein-2分类
生物科学引用本文复制引用
程海兵..人脂肪干细胞在骨组织工程中应用的研究进展[J].组织工程与重建外科杂志,2011,7(4):231-234,4.基金项目
上海市自然科学基金(044119617). （044119617）
