中国组织工程研究与临床康复2011，Vol.15Issue(26)：4829-4832,4.DOI:10.3969/j.issn.1673-8225.2011.26.020
去卵巢骨质疏松模型大鼠L4脊椎骨的应力松弛与蠕变
L4 vertebra stress relaxation and creep properties in ovariectomized rats with osteoporosis
张翘 1张忠君 2李新颖1
作者信息
- 1. 吉林大学中日联谊医院,吉林省长春市,130031
- 2. 解放军空军航空大学基础部,吉林省长春市,130022
- 折叠
摘要
Abstract
BACKGROUND: For the prevention and treatment of osteoporosis, it is necessary to understand the relationships of the creep and stress relaxation of the spine with time in ovanectornized ratsOBJECTIVE: To observe the osteoporosis effects on the viscoelastic properties of load-bearing bone of ovanectomized female ratsMETHODS: Forty-four Wistar female rats were divided into control and osteoporosis model groups Rats in the model group were ovanectomized at 0 week Stress relaxation trial with 1%/s strain rate and creep experiment with 0 01 Mpa/s stress increasing rate 100 data were collected within 7 200 secondsRESULTS AND CONCLUSION: The amount of stress relaxation and creep on L4 segment within 7 200 seconds was higher in the control group than the model group (P＜0.05) The stress relaxation curve changed in logarithmic manner, and the creep curve changed in exponential manner The viscoelastic properties of ovanectomized rats with osteoporosis have changes.关键词
去卵巢/骨质疏松/L4椎骨/流变特性/大鼠分类
医药卫生引用本文复制引用
张翘,张忠君,李新颖..去卵巢骨质疏松模型大鼠L4脊椎骨的应力松弛与蠕变[J].中国组织工程研究与临床康复,2011,15(26):4829-4832,4.
