摘要
Abstract
Objective To investigate the related factors affecting the hematoma absorption rate in patents with primary intracerebral hemorrhage. Methods The clinical data of 56 patients with primary intracerebral hemorrhage (hematoma volume 2. 0 to 33. 4 mL) treated with conservative medical therapy were analyzed retrospectively. The factors affecting the hematoma absorption rate were investigated. The hematoma volumes were calculated with Tada Formula Measurement. The hematoma absorption rate ( mL/ d) = the initial hematoma volume-hematoma volume after the first CT reexamination/time interval. Results <X>The hematoma absorption rate was 0. 13 - 1. 90 mL per day (mean 0. 58 ±0. 31mL per day). (Dunivariate analysis showed that the hematoma absorption rate at the different area of the brain was various; Absorption rate of hematoma volume between 10 mL to 30 mL was faster than that < 10 mL or > 30 mL. The patients with history of excessive alcohol drinking, hypertension, abnormal liver function, increased systolic blood pressure on admission, and complicated with infection night slowed down the hematoma absorption rate. The patients with increased plasma D-dimer level and administration of mannitol would increased the hematoma absorption rate. The hematoma absorption rate was negatively correlated with the levels of cholesterol and blood urea nitrogen (r = - 0. 789, r = - 0. 586 ) , and was positively correlated with the high-density lipoprotein (r = 0. 681, all P<0.05). ? Gender, age, diabetes, history of stroke,history of smoking, bleeding into the ventricle, shape of hematoma , state of consciousness on admission, plasma fibrinogen, fasting glucose, low sodium, low potassium, the diastolic blood pressure on admission, use of dehydrated agents, mean arterial blood pressure during the hospitalization were not the affecting factors for the rate of hematoma absorption. @Multiple stepwise regression analysis showed that the hematoma absorption rate was positively correlated with the levels of plasma D-dimer and high-density lipoprotein, and was negatively correlated with the cholesterol level, high systolic blood pressure on admission, blood urea nitrogen level and complicated with infection. ?The hematoma absorption rate was not associated with the changes of NIHSS scores from the patients'admission to the first head CT reexamination (r =0. 083). Conclusion Plasma D-dimer level, serum urea nitrogen level, the systolic blood pressure on admission, lipid level, and complicated infection may be the independent affecting factors for influence the hematoma absorption rate after intracerebral hemorrhage.关键词
脑出血/血肿/吸收/影响因素Key words
Intracerebral hemorrhage/ Hematoma/ Absorption/ Affecting factors
