中国脑血管病杂志2011，Vol.8Issue(10)：522-525,4.DOI:10.3969/j.issn.1672-5921.2011.10.005
大脑中动脉供血区大面积脑梗死患者脑疝危险因素的分析
Analysis of the risk factors for cerebral hernia in patients with large area infarction of middle cerebral artery
石丹 1许岩 1杜宇平 1李洪标 1万琦 1诸兴明1
作者信息
- 1. 214044无锡,解放军第一○一医院(太湖医院)神经内科
- 折叠
摘要
Abstract
Objective To analyze the risk factors for fatal brain edema in patients with large area infarction of middle cerebral artery ( malignant middle cerebral artery territory infarction, MMCI). Methods The clinical data of 137 patients with MMCI from August 2002 to January 2011 were analyzed retrospectively. They were divided into brain hernia group ( re = 48 ) and non-hernia group ( n = 89 ) according to whether they had brain hernia or not in the course of disease. The possible risk factors for brain edema were analyzed. Results Forty-six patients were died, 36 patients in the hernia group and 10 patients in the non-hernia group; 91 patients survived, but all left limb paralysis. ①The univariate analysis showed that the percentage of atrial fibrillation, staring, smoking, high systolic blood pressure, National Institutes of Health Stroke Scale ( NIHSS) score and barthel index ( BI) index in the hernia group were all higher than those in the non-hemia group. The differences were statistically significant (all P <0. 05) ; the Glasgow Coma Scale (GCS) score in the hernia group was lower than that in the non-hernia group (P < 0. 01). ②Multivariate logistic regression analysis showed that smoking (OR, 3. 391; 95% CI, 1. 339 to 30.505) , GCS score (OR, 0. 684, 95% CI, 0. 554 to 0. 844) and systolic blood pressure level (OR, 1.027, 95% CI, 1. 006 to 1. 049) were significantly correlated with the occurrence of brain edema. Conclusion The patients with MMCI combined with atrial fibrillation are more susceptible to acute cerebral edema caused brain hernia. Smoking, GCS score and high systolic blood pressure level may be the risk factors for cerebral hernia.关键词
脑梗死/梗死/大脑中动脉/脑水肿/危险因素Key words
Brain infarction/ Infarction,middle cerebral artery/ Brain edema/ Risk factors引用本文复制引用
石丹,许岩,杜宇平,李洪标,万琦,诸兴明..大脑中动脉供血区大面积脑梗死患者脑疝危险因素的分析[J].中国脑血管病杂志,2011,8(10):522-525,4.
