中国听力语言康复科学杂志Issue(5)：12-15,4.DOI:10.3969/j.issn.1672-4933.2011.05.002
重度单侧感音神经性耳聋患者听觉传导通路激活的fMRI研究
An fMRI Study of Auditory Pathway Activation in Severe Unilateral Sensorineural Hearing Loss
摘要
Abstract
Objective To study the activation range and intensity of each nucleus of the auditory pathway under sound stimulation in patients with severe unilateral sensorineural hearing loss. Methods The hearing-impaired and normal-hearing control groups were stimulated to the left and right ear separately. The subjects were divided into 4 groups and tested. The fMRI data were then processed and analyzed. Results ?Given the stimulation, the 4 groups showed different degrees of activation in the nuclei of auditory pathway. ?There were significant differences in the activation of auditory cortex, medial geniculate body and inferior colliculus of the 4 groups under the 500 Hz and 4000 Hz pure-tone stimulation. Conclusion The activation range and intensity of auditory cortex under 500 Hz stimulation were greater than those under 4000 Hz stimulation. The activation range of medial geniculate body and inferior colliculus changed little while the change rate of activation intensity at 500 Hz was higher than that at 4000 Hz. The functional and structural reorganizations occurred in the auditory pathway, specifically in the auditory cortex.关键词
功能性核磁共振成像/重度单侧感音神经性耳聋/听觉传导通路Key words
Functional magnetic resonance imaging(fMRI)/ Severe unilateral sensorineural hearing loss/ Auditory pathway引用本文复制引用
魏倩,李强..重度单侧感音神经性耳聋患者听觉传导通路激活的fMRI研究[J].中国听力语言康复科学杂志,2011,(5):12-15,4.基金项目
国家社会科学基金(项目编号:10CYY016) （项目编号:10CYY016）
