现代妇产科进展2011,Vol.20Issue(9):707-709,3.
黄体中期补充戊酸雌二醇对IVF-ET结局的影响
Influence of oestradiol valerate supplementation on pregnancy outcomes during mid-luteal phase in IVF-ET cycles
张敏 1邱耀芳 1孙波澜 1叶丽霞 1吴小梅1
作者信息
- 1. 深圳市第五人民医院罗湖区人民医院生殖医学中心,深圳,518001
- 折叠
摘要
Abstract
Objective; To evaluate the influence of oestradiol valerate supplementation on pregnancy outcomes during mid-luteal phase in IVF-ET cycles. Methods ;772 long protocol IVF-ET or ICSI-ET cycles in 2009 and 2010(from January to November in each year) were retrospectively analyzed. The patients were divided into 4 groups ( A, B, C, D ) , according the ratio of E2 levels from the 7th day after embryo transfer to HCG administration. The patients from 2009 did not received oral oestradiol valerate during mid-luteal phase. The patients from 2010 received oral oestradiol valerate during mid-luteal phase. The rates of clinical pregnancy and abortion were compared among the groups in two years. Result; The rates of clinical pregnancy did not differ significantly among 4 groups in two years (P>0.05). The abortion rates of patients with 3 ~ 6mg/ d of oestradiol valerate supplementation during mid-luteal phase in Group C and D (the ratio of E2 levels from the 7th day after embryo transfer to HCG administration is less than 30% ) were lower than those patients who did not received oestradiol valeratein(P<0.01). Conclusions: Oestradiol valerate supplementation during mid-luteal phase cannot improve the rate of clinical pregnancy in IVF-ET,but can reduce the rate of abortion.关键词
受精/体外/胚胎移植/雌激素/黄体中期Key words
Fertilization in vitro/ Embryo transfer/Estrogen/ Mid-luteal phase分类
医药卫生引用本文复制引用
张敏,邱耀芳,孙波澜,叶丽霞,吴小梅..黄体中期补充戊酸雌二醇对IVF-ET结局的影响[J].现代妇产科进展,2011,20(9):707-709,3.