中国当代儿科杂志2011，Vol.13Issue(10)：811-813,3.
支气管哮喘患儿的神经应激反应与气质的相关性研究
Correlation of the stress reaction and temperament in children with bronchial asthma
张海燕 1陆敏 2刘贺临 1高琼 1刘义红1
作者信息
- 1. 华中科技大学医学院附属孝感医院儿科,湖北,孝感,432000
- 2. 孝感市妇幼保健院儿科,湖北,孝感,432100
- 折叠
摘要
Abstract
Objective To study the correlation between the temperament dimension and the stress reaction in children with bronchial asthma. Methods Between February 2008 and May 2010, two hundred and twenty children with bronchial asthma and aged from 3-7 years were enrolled (asthma group). Eighty children without asthma, respiratory tract infections, serious body diseases and mental disorders who were age- and gender-matched to the asthma group served as the control group. The Carry temperament rating scales were filled by the children' s parents from the asthma and control groups. The serum levels of cortisol at 8am and 4pm and nerve growth factor ( NGF) were measured by immunochemiluminescent assays. Results The scores of the rhythmicity and persistence in temperament dimensions in the asthma group were significantly lower than those in the control group; in contrast, the scores of phobotaxis, response intensity, emotion entity, adaptability and attention dispersion in the asthma group were significantly higher than those in the control group (P<0.05). The levels of serum cortisol at 8am and 4pm were lower, while the serum level of NGF was higher in the asthma group than those in the control group ( P < 0. 05 ). The scores of response intensity, emotion entity and adaptability in temperament dimensions were positively correlated with serum NGF level (r =0. 348,0.468,0. 195, respectively; P<0.05) , and inversely correlated with serum cortisol level at 8 am (r= -0.297, -0.462, -0. 152, respectively; P < 0.05 ) in the asthma group. Conclusions The temperament dimension is associated with the stress reaction in children with bronchial asthma. This provides a basis for the treatment of bronchial asthma by neuropsychological adjustment.关键词
哮喘/皮质醇/神经生长因子/气质/儿童Key words
Asthma/Cortisol/Nerve growth factor/Temperament/Child分类
医药卫生引用本文复制引用
张海燕,陆敏,刘贺临,高琼,刘义红..支气管哮喘患儿的神经应激反应与气质的相关性研究[J].中国当代儿科杂志,2011,13(10):811-813,3.
