重庆医学2011，Vol.40Issue(33)：3375-3377,3.DOI:10.3969/j.issn.1671-8348.2011.33.021
叹气法肺复张对肺外源性和肺内源性急性呼吸窘迫综合征疗效的影响
Effects of sigh in patients with acute respiratory distress syndrome caused by extrapulmonary and pulmonary disease
摘要
Abstract
Objective To assess the effects of sighs with low tidal volume(VT) ventilation on improving gas oxygenation and respiratory mechanics in patients suffering from acute respiratory distress syndrome(ΛRDS) , and to assess the effects of sighs on he-modynamics. Methods Thirty patients with ARDS (ΛRDSexp group, ΛRDSp group)admitted from November 2006 to November 2008 in ICU of Hebei provincial people s hospital were enrolled in the study. We provided the kind of mechanical ventilation that is small VT and a suitable PEEP with sighs. Results Compared with baselines, PaO2/FiO2 was significantly increased in the two groups in sigh period(P＜0. 05) ,and ARDSexp group was higher then ARDSp group(P＜0. 05). Static compliance(Cstat) increased markedly after sigh in the two groups(P＜0. 05). There were no significant differences between baselines and sigh period for hemo-dyna mics[heart rate (HR) ,mean arterial pressure(MΛP) and central venous pressure(CVP)]. Barotrauma did not occur in all patients. Conclusion Persistent sigh significantly improve oxygenation and compliance of respiratory system. Persistent sigh is safe and simple. This study also suggests that patients with ARDS caused by extrapulmonary disease respond better to sigh than ARDS caused by pulmonary disease.关键词
呼吸窘迫综合征,成人/肺保护性通气/肺复张/叹气法Key words
respiratory distress syndrome,adult/ lung protective ventilation/ recruitment maneuver/ sigh引用本文复制引用
杜全胜,申丽旻 ,刘秀清,张爱丽,赵鹤龄,任珊..叹气法肺复张对肺外源性和肺内源性急性呼吸窘迫综合征疗效的影响[J].重庆医学,2011,40(33):3375-3377,3.基金项目
河北省卫生厅2007年医学科学研究重点指导性课题(07156) （07156）
河北省科学技术研究与发展计划项目(10276105D-67). （10276105D-67）
