EB病毒阴性的侵袭性NK细胞白血病1例报道并文献复习OA北大核心CSCDCSTPCD
Aggressive natural killer cell leukemia with epstein-barr virus negativity:a case report and literature review
目的 通过报道1例EB病毒阴性的侵袭性NK细胞白血病(ANKL)患者诊治,以提高对该病的认识.方法 对1例新近诊断的EB病毒阴性的ANKL患者的临床资料进行分析,并复习国内外相关文献.结果 该病临床表现为持续高热及肝、脾、淋巴结肿大;外周血、骨髓涂片大颗粒淋巴细胞增多;免疫表型CD2(+)、表面CD3(―)、胞质CD3(+)、CD56(+)、CD57(―);TCR基因、IgH基因重排均为阴性.结论 ANKL恶性度高,病情发展呈高度侵袭性,对化学治…查看全部>>
Objective Through one case of aggressive natural killer cell leukemia(ANKL) with epstein-barr virus negativity report to improve the recognization of this desease. Methods The clinical datum of one case of aggressive natural killer cell leukemia was analyzed and the related literature was reviewed. Results The case presented with persistence ardent fever,hepatosplenomegly and lymphadenopathy; Increasing large granular lymphocytes could be finded in bone marr…查看全部>>
张萍;罗云;陈姝;娄世锋
重庆医科大学附属第二医院血液内科,400010重庆医科大学附属第二医院血液内科,400010重庆医科大学附属第二医院血液内科,400010重庆医科大学附属第二医院血液内科,400010
诊断鉴别诊断侵袭性NK细胞白血病
diagnosis differential diagnosis aggressive natural killer leukemia diagnosis
《重庆医学》 2011 (33)
3384-3385,3388,3
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