肿瘤防治研究2011，Vol.38Issue(10)：1137-1139,3.DOI:10.3971/j.issn.1000-8578.2011.10.011
EGFR、TSLC1在不同喉病变组织中的表达及意义
Expression and Significance of EGFR and TSLC1 in Different Laryngeal Lesions
张婷婷 1崔颖 2蔡雯 3张本2
作者信息
- 1. 276800 山东日照,日照市中医院
- 2. 辽宁医学院附属第一医院耳鼻喉科
- 3. 121001 辽宁锦州,辽宁医学院耳鼻咽喉头颈外科学
- 折叠
摘要
Abstract
Objective To investigate epidermal growth factor receptor(EGFR), tumor suppressor of non-small cell lung cancer KTSLCDin the throat benign lesions and precancerous lesions and cancer of the larynx in both the rule and expression analysis of the organization. Explore glottis of mechanisms that provide for laryngeal cancer prevention. Methods Throat benign lesions, and laryngeal precancerosis with 30 cases, using immunohistochemical staining (SP) detection in which the expression of EGFR, TSL1l. Results From throat benign lesions → precancerous lesions → laryngeal of the larynx, the increasing trend of EGFR expression, the expression TSLCl dropped, the difference is statistically (P<0. 01). Laryngeal EGFR, TSLCl expression without correlation(P>0. 05). Conclusion EGFR and TSLCl in the throat by a benign lesion to precancerous lesions and cancer of the development process may play an important role关键词
EGFR/TSLC1/喉良性病变/喉癌前病变/喉癌Key words
EGFR/TSLCl/Throat benign lesions/Laryngeal precancerosis/Laryngeal分类
医药卫生引用本文复制引用
张婷婷,崔颖,蔡雯,张本..EGFR、TSLC1在不同喉病变组织中的表达及意义[J].肿瘤防治研究,2011,38(10):1137-1139,3.
