肿瘤防治研究2011，Vol.38Issue(10)：1140-1142,3.DOI:10.3971/j.issn.1000-8578.2011.10.012
基质金属蛋白酶-3和血管内皮生长因子在胃癌组织中的表达及意义
Expressions and Significance of MMP-3 and VEGF in Gastric Carcinoma
廖如奕 1牛灵2
作者信息
- 1. 830054 乌鲁木齐,新疆医科大学第一附属医院消化科
- 2. 新疆维吾尔自治区人民医院呼吸二科
- 折叠
摘要
Abstract
Objective To detect the expressions of MMP-3 and VEGF, and investigate their clinical characteristic in gastric carcinoma. Methods The study included 140 cases of gastric carcinoma as observation group, 140 cases of normal gastric mucosa as control group. The expressions of MMP-3 and VEGF were detected in two groups by FCM. We analyzed the different clinical characteristic in the observation group. Results The higher expressions of MMP-3 and VEGF were found in the observation group than that in the control group. The expressions of MMP-3 and VEGF were obviously significant in differetiation, depth and lymph metastasis. The positive correlation of MMP-3 and VEGF were found in gastric carcinoma. Conclusion The higher expressions of MMP-3 and VEGF can promote the occurrence and development in gastric carcinoma. The combined detection of MMP-3 and VEGF may be help to predict the prognosis in gastric carcinoma.关键词
胃癌/基质金属蛋白酶-3/血管内皮生长因子/流式细胞术Key words
Gastric carcinoma) MMP-31 VEGF/FCM分类
医药卫生引用本文复制引用
廖如奕,牛灵..基质金属蛋白酶-3和血管内皮生长因子在胃癌组织中的表达及意义[J].肿瘤防治研究,2011,38(10):1140-1142,3.
