中药材Issue(8)：1288-1292,5.
中药挥发油微乳与伪三元相图的研究
Study on Chinese Herbs' Volatile Oil Micro-emulsions by Means of Pseudo-ternary Phase Diagram
杨蒙蒙 1张琰 1刘新友 1张婷婷 1刘梅1
作者信息
- 1. 第四军医大学唐都医院药剂科，陕西西安710038
- 折叠
摘要
Abstract
Objective; To optimize the formulation of Chinese herbs' volatile oil micro emulsion. Methods; Sreened the formulation of blank micro-emulsion and the formulation of micro-emulsion contained volatile oil by means of pseudo-ternary phase diagram. Results; System of isopropyl myristate, polyoxyethylene hydrogenated castor oil, absolute ethyl alcohol and water could formed the largest area of micro-emulsion. The optimal formulation of micro-emulsion contained volatile oil was;volatile oil consisted of 2. 852% , isopropyl myristate 6. 65% , polyoxyethylene hydrogenated castor oil 30.42% , absolute ethyl alcohol 7. 605% and water 52.47%. Conclusions; Using pseudo-ternary phase diagram to optimize the formulation of Chinese herbs'micro-emulsion is scientific and feasible. The volatile oil's solubility is also increased by made of oil-in-water type micro-emulsion and insured the stability.关键词
中药挥发油/微乳/伪三元相图Key words
Chinese herbs' volatile oil/ Micro-emulsion/ Pseudo-ternary phase diagram分类
医药卫生引用本文复制引用
杨蒙蒙,张琰,刘新友,张婷婷,刘梅..中药挥发油微乳与伪三元相图的研究[J].中药材,2011,(8):1288-1292,5.
