物理化学学报2011，Vol.27Issue(8)：1919-1925,7.
pH响应型P(HEMA/MAA)纳米微凝胶分散液的凝胶化行为和流变性能
Rheological Properties and Gelation of pH-Responsive P(HEMA/MAA) Nano-Microgel Dispersions
摘要
Abstract
Poly((2-hydroxyethyl methacrylate)-co-(methacrylic acid)) (P(HEMA/MAA)) microgels with potential application in the restoration of damaged tissue were prepared. The phase transition behavior of P(HEMA/MAA) microgel dispersions at different pH values and concentrations as well as rheological properties of diluent and concentrated dispersions were investigated by tube inversion measurements and rheometry, respectively. The mechanism of the pH-induced physical gel phase transition was discussed. The results indicate that P(HEMA/MAA) microgel dispersions at a given concentration can be transformed into a macroscopic gel for gelation at a physiological pH. The mechanical strength of the P(HEMA-co-MAA) macroscopic gel (nHEMA/nMAA=8/2, pH=7.0) is the best and the elastic modulus (G') value can reach 7.58 ×103 Pa. The swelling effects of the P(HEMA/MAA) microgel are different under different conditions, which results in a variety of apparent viscosities for the diluent dispersions. We deduce that the swelling behavior of the microgel particles can be divided into three stages from the outer parts of the particles to the inner parts. The gelation transitions of the concentrated dispersions are caused synergistically by space electrostatic interactions and hydrogen bonds of the neighboring microgel particles or between microgel particles and water molecules.关键词
凝胶化/P(HEMA/MAA)微凝胶/pH响应性/分散液浓度/弹性模量Key words
Gelation/ P(HEMA/MAA) microgel/ pH-responsive/ Concentration of dispersion/ Elastic modulus分类
化学化工引用本文复制引用
申迎华,刘慧敏,李国卿,翟志国,树学峰,台秀梅..pH响应型P(HEMA/MAA)纳米微凝胶分散液的凝胶化行为和流变性能[J].物理化学学报,2011,27(8):1919-1925,7.基金项目
山西省自然科学基金(2010011032-2)和山西省研究生优秀创新项目(20103036)资助 （2010011032-2）
