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Racl及Ki-67因子在人翼状胬肉中的表达

顾秋艳

中国美容医学2011,Vol.20Issue(10):1566-1568,3.
中国美容医学2011,Vol.20Issue(10):1566-1568,3.

Racl及Ki-67因子在人翼状胬肉中的表达

Racl and Ki-67 factor expression in human pterygium

顾秋艳1

作者信息

  • 1. 邢台医学高等专科学校眼科教研室 河北邢台 054000
  • 折叠

摘要

Abstract

Objective To study the expression of Rac -1 and Ki -67 in primary pterygium by immunohistochemica method. The relationship among them was analyzed. The possibility was discussed utilizing of Rac1 and Ki-67 as s marker for assessment of biological characteristics of pterygium and we tried to provide reference for clinical practice Methods Immunohistochemistry was used to measure the expression of Rac1 and Ki -67 in 39 cases of primary pterygium and 12 cases of normal conjunctiva. Results The expression of Rac-1 and Ki-67 in primary pterygiurr were higher than normal conjunctiva with the difference being significant (Z=-3.386,Z=2.707, both P<0.05). Expressior of Rac1 and Ki-67 expression was negatively correlated (r=0.384,P>0.05). Conclusion Rac1 and Ki-67 expression ir the height of pterygium, suggesting that pterygium in the cytoskeleton, basement membrane breakdown and eel proliferation activity in metabolic changes.

关键词

Racl/Ki-67/翼状胬肉/免疫组织化学

Key words

Rac1/ Ki-67/ pterygium/immunohistochemistry

分类

医药卫生

引用本文复制引用

顾秋艳..Racl及Ki-67因子在人翼状胬肉中的表达[J].中国美容医学,2011,20(10):1566-1568,3.

中国美容医学

1008-6455

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