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济南汉族群体5个Y-SNP位点的多态性分析

韩淑毅 高洪梅 张茂修 郑燕 郏雁飞 丁卜同 汪运山

法医学杂志2011,Vol.27Issue(3):205-207,210,4.
法医学杂志2011,Vol.27Issue(3):205-207,210,4.DOI:10.3969/j.issn.1004-5619.2011.03.013

济南汉族群体5个Y-SNP位点的多态性分析

Polymorphic Analysis of 5 Y-SNP Loci in Han Population of Jinan

韩淑毅 1高洪梅 1张茂修 2郑燕 1郏雁飞 2丁卜同 1汪运山1

作者信息

  • 1. 山东大学附属济南市中心医院,山东济南250013
  • 2. 济南迪恩法医司法鉴定所,山东济南250013
  • 折叠

摘要

Abstract

Objective To investigate polymorphism distribution of the 5 Y-SNP loci in Jinan Han popula tion, and evaluate their potential in forensic application. Methods Genotyping of 5 Y-SNP loci (M89, M9, M122, M134, M95) were executed in the sample of 103 unrelated Chinese male individuals in Jinan Han population by using fragment length discrepant allele specific PCR (FLDAS-PCR). Results In 5 Y-SNP loci, genetic polymorphism were identified in Jinan Han population, and the ranges of gene diversity (GD) were 0.093 3-0.491 2. Twenty different haplotypes were observed and the haplotypes diversity (HD) was 0.867 9. Six different haplogroups were detected according to international association of Y chromosome nomenclature. Conclusion Five Y-SNP loci and their haplogroups in Jinan Han population are highly polymorphic, which can provide more information for the genetic structure analysis and forensic genetics research in the region.

关键词

法医遗传学/多态性,单核苷酸/Y染色体/汉族

Key words

forensic genetics/ polymorphism, single nucleotide/ Y chromosome/ Han nationality

分类

社会科学

引用本文复制引用

韩淑毅,高洪梅,张茂修,郑燕,郏雁飞,丁卜同,汪运山..济南汉族群体5个Y-SNP位点的多态性分析[J].法医学杂志,2011,27(3):205-207,210,4.

基金项目

济南市科技局项目(066007) (066007)

法医学杂志

OACHSSCDCSCDCSTPCDMEDLINE

1004-5619

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