临床误诊误治2011,Vol.24Issue(10):12-14,3.
冠心病患者红细胞体积分布宽度变化及其临床意义
The Changes and Clinical Application Value of Red Blood Cell Distribution Width in Patients with Coronary Heart
黄媛 1陈建魁 1于农 1宋世平 1尹秀云 1金欣 1杜宇1
作者信息
- 1. 100071北京,军事医学科学院附属医院检验科
- 折叠
摘要
Abstract
Objective To observe the changes of red blood cell distribution width ( RDW ) in patients with coronary heart disease (CHD) and to evaluate its clinical application value. Methods SIS patients with CHD admitted into our hospital were enrolled and divided into angina pectoris group(n =365), acute myocardial infarction( AMI) group(n = 103) and acute heart failure(AHF) group (u =47) , and 430 healthy controls were selected as control group. The levels of Hemoglobin Hb), RDW, High-sensitive C-reaction protein (hs-CRP) and B-type natriuretic peptide(BNP) were measured. Results Compared with that in the control group, the level of RDW in 515 patients with CHU was significantly increased, and the difference was significant P <0. 01); the level of RDW in AHF group was higher than that in angina pectoris group, and the difference was significant/* <0. 05). When participants were grouped according to quartiles of RDW, incidence rates of AHF and AIM were increased gradually and associated with the increasing of RDW level. Higher RDW was associated with increased mortality rate in patients with CHD. The level of RDW was positively related to the level of BNP(r =0.415, P < 0.01), and was somewhat positively related to hs-CRP (r =0.234, P<0.01). Conclusion RDW may be an independent factor of prognosis of CHD, which may be helpful in judging the prognosis of CHD.关键词
冠状动脉疾病/红细胞体积分布宽度/利钠肽,脑/C反应蛋白/预后/判断Key words
Coronary artery disease/ Red blood cell distribution width/ natriuretic peptide, brain/ C-reaction protein/ Prognosis/ Judgment分类
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黄媛,陈建魁,于农,宋世平,尹秀云,金欣,杜宇..冠心病患者红细胞体积分布宽度变化及其临床意义[J].临床误诊误治,2011,24(10):12-14,3.