昆明医学院学报2011，Vol.32Issue(9)：92-95,4.
878株鲍曼不动杆菌的耐药分析及流行调查
Resistance Analysis and Epidemiological Survey of 878 Acinetobacter Baumannii Solates
许云敏 1晋臻 1杜艳 1陈正辉 1陈瑞春 1邵天波1
作者信息
- 1. 昆明医学院第一附属医院检验科,云南昆明 650032
- 折叠
摘要
Abstract
Objective To provide effective laboratorial proof and control hospital infection by investigating the distribution and drug resistance of Acinetobacter baumannii and analyzing resistance profiles. Method The distribution, drug resistance and resistance profiles including Aztreonam (A) , Ampicillin (P ) , Ciprofloxacin (C) , Meropenem (M) , Ceftazidime (F) and Imipenem (I) of Acinetobacter baumannii clinical isolates in our hospital from Jan. 2008 to Jun. 2011 were reviewed and analyzed by WHONET 5.5 software. Results 878 Acinetobacter baumannii strains were found, in which 84% were respiratory tract specimens, and most strains were in ICU. Acinetobacter baumannii 's infection rate and drug resistance rates to 16 clinical common antibiotics was rising year by year, particularly resistance rates to Imipenem and Meropenem were up to 84.4% and 87.5% respectively. Resistance profiles of Acinetobacter baumannii had 67 kinds, in which three phenotypes: (1) "APC-FI" (ATM, AMP, CIP, CAZ, IPM: all resistance, MEM: not determined), (2) "APCMFI" (ATM, AMP,CIP,MEM,IPM all resistance were mainly phenotypes. The infection rate of the two phenotypes was 19%, and 15%, respectively. Conclusion Infection rate of Acinetobacter baumannii is rising year by year, its resistant rates to common antibiotics show an upward trend and new phenotype start to prevalent.关键词
鲍曼不动杆菌/耐药/抗生素/耐药谱Key words
Acinetobacter baumannii/Drug-resistance/Antibiotics/Resistance profies分类
医药卫生引用本文复制引用
许云敏,晋臻,杜艳,陈正辉,陈瑞春,邵天波..878株鲍曼不动杆菌的耐药分析及流行调查[J].昆明医学院学报,2011,32(9):92-95,4.
