华南农业大学学报2011,Vol.32Issue(3):122-124,3.
2-胺乙基苯并咪唑金属配合物的合成、表征和抑菌活性研究
Synthesis, Characterization and Antibacterial Activity of ThreeMetal Complexes Containing 2-Aminoethylbenzimidazole
摘要
Abstract
2-Aminoethylbenzimidazole (AEB) and its three transitional metal complexes, metal ion of copper ( Ⅱ), nickel ( Ⅱ ) or cobalt ( Ⅱ ) , were synthesized and characterized by elemental analysis, molar conductivity, IR and UV-Vis. The chemical formulae of the three complexes are [Cu( AEB)2Cl] Cl (complex 1), [ Ni (AEB) 3 ] Cl2 (complex 2) and [ Co (AEB) 3 ] Cl2 (complex 3). The three complexes were assayed against Escherichia coli, Staphylococcus aureus, Bacillus subtilis and B. thuringiensis by the plate-pervasion method. The results show that the coordination of AEB to the metal ion enhances the antibacterial activity at moderate and high tested concentrations although the AEB has no inhibition to the four tested bacterium at all tested concentrations.关键词
2-胺乙基苯并咪唑/金属配合物/抑菌活性Key words
2-aminoethylbenzimidazole/ metal ( Ⅱ) complex/ antibacterial activity分类
化学化工引用本文复制引用
周晓华,吴海雷,骆锦强,黄小悦..2-胺乙基苯并咪唑金属配合物的合成、表征和抑菌活性研究[J].华南农业大学学报,2011,32(3):122-124,3.基金项目
广东省科技计划项目(2009B020310013) (2009B020310013)
华南农业大学校长基金(2008X013) (2008X013)
华南农业大学“211工程”三期重点建设项目(2009B010100001) (2009B010100001)