心理学报2011，Vol.43Issue(7)：792-797,6.DOI:10.3724/SP.J.1041.2011.00792
慢性军事应激致军人海马形态、认知功能和应对方式的变化
Changes in Hippocampus Morphology, Cognitive Function and Coping Style Induced by Chronic Military Stress
摘要
Abstract
Many organic functions will be changed undergoing chronic strong stress, especially in the continuous activation of the HPA axis, which results in successive high level of glucocorticoid in blood. Afterward it will make hippocampal neurons become atrophic and cognitive function impairment, which has been confirmed in laboratory. This investigation studied the morphological changes of hippocampus, cognitive functions and coping styles undergoing the chronic military stress.The present investigation was intended principally to study the characteristic changes in hippocampus morphology (MRI), cognition (simple and complex cognitive function), psychological trait (State-trait Anxiety Inventory, STAI) and coping style (Characteristic Coping Style Questionnaire, CCSQ) in chronic strong military stress. 572 soldiers were divided into the group of investigation (A) in accordance with Anxiety factor score in SCL-90 and the control group (B). In group A, very soldier who's the anxiety factor score was over 3. In control group, the soldiers were selected via matching method according to that in group A.The results showed that the level of plasma cortisol in group A and B were higher significantly higher than normal and that in group A was were higher significantly higher than group B. After standardization, there was no significant structural difference between right and left hippocampus in same subject. But, the hippocampal structural atrophy in group A and there was significant structural difference between group A and group B. In cognitive function, there were no significant change in the simple cognitive assignments between group A and B but significant difference in negative coping style between group A and B. In STAI, the estimative scores of state anxiety and trait anxiety in group A were significantly higher than group B and normal. The estimative scores of state anxiety in group B were significantly higher than normal. The estimative score of positive coping style in group A was significantly lower and that of negative coping style was significantly higher than group B and normal. The estimative score of positive coping style in group B was significantly higher than normal.The present findings indicated that chronic strong military stress can induce hippocampal structural atrophy and insult in characteristic changes in some psychological trait, cognitive function and behavior.关键词
军事应激/状态-特质焦虑/应对方式/磁共振成像/血皮质醇/认知功能/海马Key words
military stress/ STAI/ CSQ/ MRI/ Cortisol/ cognitive function/ hippocampus分类
社会科学引用本文复制引用
王丽杰,孙秋德,严进,刘爱丽,董建树,刘佳佳,王建平..慢性军事应激致军人海马形态、认知功能和应对方式的变化[J].心理学报,2011,43(7):792-797,6.基金项目
国家科技支撑计划(2009BAI77B04) （2009BAI77B04）
国家高技术研究发展计划(863计划2008AA022602) （863计划2008AA022602）
上海市教委科研创新重点项目(11ZS79) （11ZS79）
国家新药创制科技重大项目(2008ZXJ09014-011). （2008ZXJ09014-011）
