摘要
Abstract
Objective To explore the value of cytological and histological diagnosis in the peritoneal and retroperitoneal space-occupying lesions by EUS-guided fine-needle aspiration (EL'S-FNA). Methods 103 patients with peritoneal and retroperitoneal space-occupying lesions underwent EUS-FNA biopsy detection, the results of cytological diagnosis of different sites were compared with that of hislological diagnosis according to the categorizations of madden cytological smears and paraffin sections, and the results, which were nonconformity, were analyzed. Results Among 103 patients with peritoneal and retroperitoneal space-occupying lesions, 43 had lesions on peritoneal and retroperitoneal lymph nodes, with 29 on pancreas, 20 on gastrointestinal tract, and 11 on liver. EUS-FNA Cytological diagnosis was coincident with histological diagnosis in 64 patients (62. 14% ) , and not coincident in 39 patients (37.86%). 61 patients was diagnosed as having benign lesions by cytological detection. Among those who were detected by histology, 44 were diagnosed as having benign lesions, 9 were atypia, and 8 were malignant; 61 patients was diagnosed as having alypia lesions by cytological detection. Among those who were detected by histology, 5 were diagnosed as having benign lesions, 6 were atypia, and 14 were malignant; 17 patients was diagnosed as having malignant lesions by cytological detection. Among those were detected by histology, 2 were diagnosed as having benign lesions, 1 was atypia, and 14 were malignant. Tested by kappa consistency check, no significant difference was found between cytological diagnosis and histological diagnosis in gastrointestinal tract space-occupying lesions; there were significant differences between cytological diagnosis and histological diagnosis in other sites (P < 0. 05). There were significant differences between EUS-FNA cytological diagnosis and histological diagnosis in peritoneal and retroperitoneal space-occupying lesions ( P < 0.001). Compared with the two diagnosis methods, the sensitivity of EUS-FNA cytological diagnosis was 67. 3% , specificity was 86. 3% , Positive predictive value was 83.3% , and negative predictive value was 72.1% . Conclusion Cytological diagnosis and histological diagnosis by EUS-FNA may be more valuable in diagnosis of peritoneal and retroperitoneal space-occupying lesions, which can confirm and complement each other.关键词
腹腔/腹膜后肿瘤/活组织检查,针吸/细胞学技术:诊断Key words
Peritoneal cavity/ Retroperitoneal neoplism/ Biopsy, needle/ Cytological technique/ Diagnosis分类
医药卫生
