中德临床肿瘤学杂志（英文版）2011，Vol.10Issue(12)：683-686,4.DOI:10.1007/s10330-011-0878-4
同步放化疗Ⅲ-Ⅳa期鼻咽癌的临床观察
The clinical effects of concurrent radiochemotherapy in cases suffered from stages III to IVa nasopharyngeal carcinoma
Hongsheng Yu 1Wei Zhang 1Li Yu1
作者信息
- 1. Department of Oncology, The Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China
- 折叠
摘要
Abstract
Objective: The aim of the study was to investigate the clinical effects of concurrent radiochemotherapy in treating while Group CCRT was delivered three cycles chemotherapy of PF (DDP + 5-Fu) regimen or PLF (DDP + 5-Fu + CF) regimen.Results: The complete remission rate and total remission rate of Group CCRT were higher than those of Group RT, and the by life table method, in Group CCRT, it was higher than that of Group RT and the difference was of statistical importance (χ2= 4.24, P < 0.05). The 3-year overall survival (OS) rate, nasopharyngeal control rate and cervical lymph nodes' control rate < 0.05). The 5-year overall survival (OS) rate and metastasis-free rate of Group CCRT were higher than those of Group RT CCRT were obviously higher than those in Group RT, and the difference of gastrointestinal reaction was of statistical importance (χ2 = 11.70, P < 0.05). Conclusion: This study has demonstrated that concurrent radiochemotherapy can improve the remission rate, overall survival rate and locally control rate. The toxicities of concurrent radiochemotherapy can be tolerated by the patients.关键词
nasopharyngeal carcinoma (NPC)/ concurrent radiochemotherapy/ radiotherapy/ chemotherapy/ remission rate/ survival rate/ toxicityKey words
nasopharyngeal carcinoma (NPC)/ concurrent radiochemotherapy/ radiotherapy/ chemotherapy/ remission rate/ survival rate/ toxicity引用本文复制引用
Hongsheng Yu,Wei Zhang,Li Yu..同步放化疗Ⅲ-Ⅳa期鼻咽癌的临床观察[J].中德临床肿瘤学杂志（英文版）,2011,10(12):683-686,4.
