中国组织工程研究与临床康复2011，Vol.15Issue(42)：7835-7838,4.DOI:10.3969/j.issn.1673-8225.2011.42.011
丝蛋白应用于牙周组织工程的可行性
Feasibility of silk fibroin proteins used in periodontal tissue engineering
崔菊萍 1王新 1邹建明1
作者信息
- 1. 无锡市第三人民医院口腔科,江苏省无锡市,214031
- 折叠
摘要
Abstract
BACKGROUND: Sik fibroin protein is a new type of bin mate rial that is beneficial to the adhesion and growth of skin cells, fibroblasts, osteoblasts. endothelial cells, and glial cells.OBJECTIVE: To evaluate the feasibility of the silk fibroin protein as an ideal scaffold material for periodontal tissue engineering. METH ODS: Sik fibroin protein composite scaffolds were prepared through afreeze-drying method. The periodontal ligament cells (2 x 10(7)/L) were collected and seeded on three-dimensional framework of sik fibroin protein (1%, 10%, 50%, 100%). The cell growth and the influences of the sik fibroin protein extracts on cell proliferation and differentiation were observed. RESULT SAND CONCLUSION: The periodontal ligament cells adhered and proliferated on the three-dimensionalframafljokof sik fibroin protein, the different concentrations of sik fibroin protein extracts had no influences on the cell proliferation and differentiation. Silk fibroin protein can be used as an ideal scaffold material for cell adhesion and growth in periodontal tissue engineering.关键词
丝蛋白/支架材料/牙周膜细胞/牙周组织工程/口腔生物材料分类
基础医学引用本文复制引用
崔菊萍,王新,邹建明..丝蛋白应用于牙周组织工程的可行性[J].中国组织工程研究与临床康复,2011,15(42):7835-7838,4.
