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提高乳癌HER2阳性检出率的免疫组化染色方法 探讨

赵洁 王继纲

青岛大学医学院学报2011,Vol.47Issue(6):525-526,2.
青岛大学医学院学报2011,Vol.47Issue(6):525-526,2.

提高乳癌HER2阳性检出率的免疫组化染色方法 探讨

THE APPROACH OF RAISING HER2 DETECTION RATE OF BREAST CANCER USING IMMUNOHISTOCHEMICAL STAINING

赵洁 1王继纲1

作者信息

  • 1. 青岛大学医学院附属医院病理科,山东青岛266071
  • 折叠

摘要

Abstract

Objective To study a immunohistochemical staining that raises the detection rate of human epidermal growth factor receptor 2 (HER2) of breast cancer. Methods Three different Methods were used to detect HER2 in 1 128 pathologically-confirmed samples of breast cancer. Results The positive rates of HER2 were significantly different among three different antigen retrieval methods (Hc = 7. 34;q=15. 59 - 66. 55;P<0. 01). Conclusion The high-pressure restoration technique is the best compared with boiling or microwave method in terms of HER2 detection.

关键词

乳腺肿瘤/HER2受体/免疫组织化学染色

Key words

breast neoplasms/ HER2 receptor/ immunohistochemical staining

分类

医药卫生

引用本文复制引用

赵洁,王继纲..提高乳癌HER2阳性检出率的免疫组化染色方法 探讨[J].青岛大学医学院学报,2011,47(6):525-526,2.

青岛大学医学院学报

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