提高乳癌HER2阳性检出率的免疫组化染色方法 探讨OACSTPCD
THE APPROACH OF RAISING HER2 DETECTION RATE OF BREAST CANCER USING IMMUNOHISTOCHEMICAL STAINING
目的 探讨提高乳癌人表皮生长因子受体2(HER2)阳性检出率的免疫组织化学染色方法.方法 采用3种不同的方法 对1 128例经病理确诊为乳癌的病人进行HER2检测.结果 3种抗原修复方法 HER2阳性结果 比较差异均有显著性(Hc=7.34,q=15.59～66.55,P＜0.01).结论 TE高压修复法乳癌HER2阳性检出率优于EDTA煮沸法,EDTA煮沸法乳癌HER2阳性检出率优于枸橼酸微波修复法.
Objective To study a immunohistochemical staining that raises the detection rate of human epidermal growth factor receptor 2 (HER2) of breast cancer. Methods Three different Methods were used to detect HER2 in 1 128 pathologically-confirmed samples of breast cancer. Results The positive rates of HER2 were significantly different among three different antigen retrieval methods (Hc = 7. 34;q=15. 59 - 66. 55;P<0. 01). Conclusion The high-pressure restoration…查看全部>>
赵洁;王继纲
青岛大学医学院附属医院病理科,山东青岛266071青岛大学医学院附属医院病理科,山东青岛266071
临床医学
乳腺肿瘤HER2受体免疫组织化学染色
breast neoplasms HER2 receptor immunohistochemical staining
《青岛大学医学院学报》 2011 (6)
525-526,2
评论