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高效液相色谱法和化学发光酶免疫分析法测定茶碱的血药浓度

范毅 刘梦

中国药业2011,Vol.20Issue(21):6-7,2.
中国药业2011,Vol.20Issue(21):6-7,2.

高效液相色谱法和化学发光酶免疫分析法测定茶碱的血药浓度

Determination of the Serum Theophylline Concentration by HPLC and CLEIA

范毅 1刘梦2

作者信息

  • 1. 江苏省泰州市人民医院,江苏泰州,225300
  • 2. 南通大学医学院,江苏南通,226000
  • 折叠

摘要

Abstract

tive Using ihe HPLC and CLEIA to determine the serum theophylline concentration and comparing the two methods.Methods Using IIPLC and CLEIA to determine the serum theopbyiline concentration of 40 patients,then comparing two restles of the two methods. Results The average recovery rate of using HPLC was 102. 77% , the intraday RSD was 0. 854 3% -1. 547 2% , the interday RSD was 1. 475 8% -4. 697 9% ; the average recovery rate of using CLEIA was 101. 17%, the intraday RSD was 2. 255 4% -7. 497 2%, the interday RSD was 0.789 8% -4.391 7%. Conclusion There was no obvious error between two methods. The results of two methods were accurate,sensitive,stable,and no error.

关键词

茶碱/高效液相色谱法/化学发光酶免疫分析法/血药浓度

Key words

theophylline/ HPLC/ CLEIA/ concentration in serum

分类

医药卫生

引用本文复制引用

范毅,刘梦..高效液相色谱法和化学发光酶免疫分析法测定茶碱的血药浓度[J].中国药业,2011,20(21):6-7,2.

中国药业

OACSTPCD

1006-4931

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