武汉工程大学学报2011，Vol.33Issue(7)：14-16,21,4.DOI:10.3969/j.issn.1674-2869.2011.07.004
点击化学反应原位制备海藻酸钠水凝胶
Preparation of alginate hydrogels via "click" chemistry
张桥 1鄢国平 1程巳雪2
作者信息
- 1. 武汉工程大学材料科学与工程学院,湖北武汉430074
- 2. 武汉大学化学与分子科学学院生物医用高分子材料教育部重点实验室,湖北武汉430072
- 折叠
摘要
Abstract
Alginate derivatives bearing side chains endowed with either azide or alkyne terminal functionality have been synthesized. When the solutions of tow derivatives were mixed together in the presence of Cu (I) catalyst, the alginate hydrogels were formed by the click chemistry between azide and alkyne. The chemical structures of the alginate derivatives and hydrogels were characterized by FT-IR. The results of SEM and swelling behavior exhibited that the hydrogels had a macroporous structure as well as pH responsive. In comparison to other methods of preparation alginate hydrogels via chemical :ross - links, this strategy is quicker and more convenience.关键词
点击化学/海藻酸钠/水凝胶/溶胀/生物材料Key words
click chemistry/ alginate/ hydrogels/ swelling/ biomaterials分类
化学化工引用本文复制引用
张桥,鄢国平,程巳雪..点击化学反应原位制备海藻酸钠水凝胶[J].武汉工程大学学报,2011,33(7):14-16,21,4.
