中国美容医学2011，Vol.20Issue(z4)：11,13,2.
皮肤原发性上皮样肉瘤病理及临床的误诊探讨
A Clinicopathologic misdiagnosis Study of Primary Epithelioid Sarcoma of Skina
赵军 1孙倩 1王雪利1
作者信息
- 1. 山东省青岛市第八人民医院病理科,266100
- 折叠
摘要
Abstract
Objective To explore the pathoclinical characteristics immunophonetype and its biological behaviour of primary epithelial sarcoma. Methods Five cases of primary epithelial sarcoma of skin were studied by using microscope observation and immunohistochemistry and analyse their characterstics of clinic,cytological smear and pathohistology. Results The group of tumors were all located in skin. Microscopically, tumor showed an invasive growth and nodulous arrangement and was made up of two kinds of cells,relativepart of cells were characterized by multangular or oval and round cell with richful eosinophilic cytoplasm,other cells were fatty and spindle just like fibroblast. The tumor nodule's central zone that was always degenerative and necrosive that surrounded by the two kinds cells. Immunohistochemically, tumor cells showedintense positive staining for EMA,Cytok-eratin and Vimentin,only showed weak positive staining for CD34and CD68,other results of immnuohistochemistry were all negative. Conclusion The tumor is quite difficult to diagnose only by microscope for its infrequency and various morphological features. No diagnostic particularity only bycelluar smear. Only based on histopathological characteristics with the results of immunohistochemistry, a definite pathological diagnosis of the tumor can be got. Its prognosis is very poor and a patient needs to have a marginal or even a radical resection.关键词
皮肤肿瘤；上皮样肉瘤；免疫组化Key words
Skin cancer/Epithelioid sarcoma/Immunohistochemistry分类
医药卫生引用本文复制引用
赵军,孙倩,王雪利..皮肤原发性上皮样肉瘤病理及临床的误诊探讨[J].中国美容医学,2011,20(z4):11,13,2.
