中药材2011,Vol.34Issue(9):1473-1477,5.
补肾活血颗粒对帕金森病患者睡眠质量的影响
Effects of Bushenhuoxue Granules on Sleep Quality in Parkinson's Patients
摘要
Abstract
Objective; To study the effects of Bushenhuoxue Granules on Parkinson's disease sleep scale ( PDSS) score in Parkinson's patients. Methods: 120 patients were enrolled and divided into two groups randomly,the control group were treated with placebo and treatment group with Bushenhuoxue Granules, both group based on Madopar treatment Double-blinded clinical trial was a-dopted in treatment period. Follow-up period for 6 months, PDSS was adopted to measure sleep condition of PD patients at baselinetime,after 3 months and after 9 months. Results: Bushenhuoxue Granules treatment group showed a higher efficacy than the placebo group in relieving the sleep disorders of Parkinson disease patients, both in treatment and follow-up period (P <0. 01 ). No adverse effects were found in this trial Conclusions: Bushenhuoxue Granules can markedly improve sleep disorders in Parkinson' s patients. The effects are stable and obvious along with the process of treatment.关键词
帕金森病/补肾活血颗粒/睡眠量表Key words
Parkinson's Disease/Bushenhuoxue Granules/Parkinson's disease sleep scale分类
医药卫生引用本文复制引用
李敏,杨明会,李绍旦,刘毅..补肾活血颗粒对帕金森病患者睡眠质量的影响[J].中药材,2011,34(9):1473-1477,5.基金项目
“十一五”国家科技支撑计划重大项目(2006BAI04A11) (2006BAI04A11)