E-cadherin、p16及Ki67在宫颈上皮内瘤变诊断中的应用OACSTPCD
Value of E-cadherin,p16 and Ki67 in diagnosis of cervical intraepithelial neoplasia
目的 探讨联合检测E-cadherin、p16、Ki67的表达在子宫颈上皮内瘤变(CIN)中的诊断价值.方法 采用免疫组织化学方法检测20例正常宫颈组织、40例CIN Ⅰ、40例CIN Ⅱ及40例CINⅢ中的E-cadherin、p16和Ki67的表达.结果 E-cadherin在正常宫颈、CIN Ⅰ、CIN Ⅱ、CINⅢ中的表达率分别为100%,80%,40%,37.5%;p16在正常宫颈、CIN Ⅰ、CIN Ⅱ、CINⅢ中的表达率分别为0,6…查看全部>>
Objective To explore the diagnostic value of the combined detection of E-cadherin,pl6 and Ki67 in cervical intraepithelial neoplasia. Methods The expression of E-cadherin,pl6 and Ki67 was measured by immnohistochemistry in 20 case of normal cervical tissues ,40 case of CIN I ,40 case of CIN II and 40 case of CIN IH respectively. Results Positive rates of E-cadherin in normal cervical epithelia,CIN Ⅰ ,CINⅡ ,CIN Ⅲwere 100% ,80% ,40% ,37. 5% ,respectively. Posi…查看全部>>
李艳东;郑建云;刘冰
西安医学院附属医院病理科,西安,710077西安医学院附属医院病理科,西安,710077西安医学院附属医院病理科,西安,710077
医药卫生
宫颈上皮内瘤变E-cadherinp16Ki67
cervical intraepithelial neoplasiaE-cadherinpl6Ki67
《山西医科大学学报》 2011 (11)
876-879,939-940,6
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