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急性肾损伤患者病因及其危险因素的临床研究

韩颖敏 吴鑫洪 肖达平 王玉

中国全科医学2011,Vol.14Issue(32):3696-3698,3.
中国全科医学2011,Vol.14Issue(32):3696-3698,3.

急性肾损伤患者病因及其危险因素的临床研究

Etiology and Risk Factors of Acute Kidney Injury

韩颖敏 1吴鑫洪 1肖达平 1王玉1

作者信息

  • 1. 318020 浙江省台州市第一人民医院肾内科
  • 折叠

摘要

Abstract

Objective To investigate the etiology and risk factors which influence the development of acute kidney injury ( AKI ) in favor of early detection, early prevention and better curative effects of the disease. Methods AKI patients from The First People's Hospital of Taizhou between Oct 2008 and Oct 2010 were enrolled in this study with the AKI etiology summarized. A total of 426 AKI patients with complete clinical data were divided into four groups: the healed group, the improved group, the invalid group, and the death group. SPSS13. 0 software was used to analyze the data of the clinical trial. We used t - test, Chi - square analysis and Logistic regression analysis to explore the risk factors which influenced the development of AKI. Results Among the 426 cases studied ( average age: 43. 3 ± 14. 8 ), 268 ( 62. 91% ) were males and 158 ( 37. 09% ) were females, with a male to female ratio of 1.7: 1. According to etiology classification, renal parenchyma injury and obstruction topped all the causes of AKI, accounting for 23. 71% and 20. 66% respectively, with infections and the use of drugs followed ( 13. 15% and 11. 50% respectively ). Logistic regression analysis revealed that multiple organ dysfunction syndromes ( MODS ), high level of serum potassium and low level of hemoglobin were influencing factors of the prognosis of AKI patients ( P <0. 01 ). Conclusion Renal parenchyma injury, obstruction, infections and the use of drugs are common causes of AKI. MODS, high level of serum potassium and low level of hemoglobin are risk factors for the prognosis of AKI patients.

关键词

急性肾损伤/病因/预后/危险因素

Key words

Acute kidney injury/ Etiology/ Prognosis/ Risk factors

分类

医药卫生

引用本文复制引用

韩颖敏,吴鑫洪,肖达平,王玉..急性肾损伤患者病因及其危险因素的临床研究[J].中国全科医学,2011,14(32):3696-3698,3.

中国全科医学

OA北大核心CSTPCD

1007-9572

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