实用妇产科杂志2011，Vol.27Issue(7)：546-549,4.
羊水板层小体计数预测胎儿肺成熟度的评价
The Evaluation of Amniotic Fluid Lameliar Body Count to Predict Fetal Lung Maturity
凤婧 1陈剑 1江咏梅 1戴维 1朱凯 1杨惠1
作者信息
- 1. 四川大学华西第二医院，四川成都610041
- 折叠
摘要
Abstract
Objective .This prospective study was designed to perform lamellar body count(LBC) of amni-otic fluid to evaluate fetal lung maturity. Methods:LBC in 82 amniotic fluid samples from 82 pregnant women (28-40 gestational weeks) were evaluated, in which 14 cases were checked two times before and after administration of dexamethasone to accelerate fetal pulmonary maturation. After delivery, each infant was eval-uated for any evidence of respiratory distress syndrome (RDS). SPSS sofeware was used to define the cutoff value of LBC to predict fetal lung immaturity and fetal lung maturity ,and the sensitivity, specificity, positive predictive value and negative predictive value were calculated. Results;The LBC increased and the incidence of RDS decreased along with the increased gestational weeks. The LBC increased significantly after the use of dexamethasone to accelerate fetal lung maturation. 11 (13.4%) infants developed RDS, 8 of them with LBC < 15 xioVL, the other three LBC were between 15 x 10'/L and 50 x10g/L. If cutoff value of LBC < 15 x 109/L was defined to predict fetal lung immaturity, the sensitivity was 72. 7%, specificity was 100%, the positive predictive value was 100% .negative predictive value was 95.9%. If cutoff value of LBC > 50 x10 9/L was defined to predict fetal lung maturity, the sensitivity was 81.7%, specificity was 100%, the positive predictive value was 100%, negative predictive value was 45. 8%. Conclusions: LBC can be used as a favorable predictor and reliable screening test for fetal lung maturity because the method is simple, quick, inexpensive,standardization and available.关键词
板层小体计数；胎儿肺成熟度；呼吸窘迫综合征；羊水Key words
Lamellar body count/Fetal lung maturity/Respiratory distress syndrome/Amniotic fluid分类
医药卫生引用本文复制引用
凤婧,陈剑,江咏梅,戴维,朱凯,杨惠..羊水板层小体计数预测胎儿肺成熟度的评价[J].实用妇产科杂志,2011,27(7):546-549,4.
