首页|期刊导航|中国神经再生研究（英文版）|Effect of escitalopram on cognitive function in depression A mismatch negativity potentials study
中国神经再生研究（英文版）2011，Vol.6Issue(31)：2441-2445,5.DOI:10.3969/j.issn.1673-5374.2011.31.008
Effect of escitalopram on cognitive function in depression A mismatch negativity potentials study
Effect of escitalopram on cognitive function in depression A mismatch negativity potentials study
摘要
Abstract
We detected the event-related potential mismatch negativity (MMN) of 30 depression patients and compared to 30 age, gender, and education-matched healthy controls. Results showed that amplitudes of frequency and duration MMN were lower in depression patients compared with control patients, indicating abnormality in auditory processing (i.e., cognitive impairment). Following escitalopram treatment for 8 weeks, the amplitudes of frequency and duration MMN were significantly increased and Hamilton Rating Scale for Depression scores were significantly decreased in depression patients. These data suggest that escitalopram can improve cognitive function of patients with depression. Further, MMN may be a useful tool for evaluating cognitive function and treatment effects.关键词
depression/event-related potentials/mismatch negativity/cognitive function/escitalopramKey words
depression/event-related potentials/mismatch negativity/cognitive function/escitalopram引用本文复制引用
Zhenhe Zhou,Guozhen Yuan,Jianjun Yao,Zaohuo Cheng..Effect of escitalopram on cognitive function in depression A mismatch negativity potentials study[J].中国神经再生研究（英文版）,2011,6(31):2441-2445,5.基金项目
the Medical Research Foundation of Jiangsu Provincial Department of Public Health,No.H201043 （）
