河北医学Issue(10)：1301-1303,3.DOI:10.3969/j.issn.1006-6233.2011.10.009
丙泊酚对急性颅脑损伤患者体内活性氧的清除作用
The Elimination Effect of Propofol on Reactive Oxygen Species in Patients with Acute Craniocerebral Injury
何二宁 1甘伟耀 1辜春霖1
作者信息
- 1. 广西南宁市第二人民医院, 广西 南宁 530031
- 折叠
摘要
Abstract
Objective: In order to investigate the elimination effect and curative effect of propofol on reactive oxygen species in patients with acute craniocerebral injury. Method: We used electron spin resonance spectroscopy to determine the plasma contents of oxygen free radical, and the chemical-high performance liquid chromatography were used to determine the nitrogen oxide and plasma contents of lipid peroxides . And then investigated the elimination effect and curative effect of propofol on reactive oxygen species in patients with acute craniocerebral injury. Result: Except of the nitrogen oxide in 2 hours after starting operation, every indexes in 2 and 4 hours after starting operation were lower, there were difference between the performance(P<0. 05). Conclusion: Propofol can clear the reactive oxygen species in patients with acute craniocerebral injury, and lessen the risk of secondary cerebral injury.关键词
丙泊酚: 急性颅脑损伤/活性氧Key words
Propofol/Acute craniocerebral injury/Reactive oxygen species引用本文复制引用
何二宁,甘伟耀,辜春霖..丙泊酚对急性颅脑损伤患者体内活性氧的清除作用[J].河北医学,2011,(10):1301-1303,3.
