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纯钛表面氧化钛和氧化锆涂层的结构性能及细胞毒性

司家文 万浩元 胡启凡 孙惠强

国际口腔医学杂志Issue(5):531-534,538,5.
国际口腔医学杂志Issue(5):531-534,538,5.DOI:10.3969/j.issn.1673-5749.2011.05.010

纯钛表面氧化钛和氧化锆涂层的结构性能及细胞毒性

Microstructure properties and cytotoxicity of titania and zirconia coating on titanium surface

司家文 1万浩元 1胡启凡 2孙惠强1

作者信息

  • 1. 山东大学口腔医学院,山东省口腔生物医学重点实验室
  • 2. 山东大学医学院临床医学系 济南250012
  • 折叠

摘要

Abstract

Objective To investigate the microstructure and properties of titania (TiO2) and zirconia (ZrO2) coated on titanium and to test its vitro cytotoxicity. Methods The titanium specimens were divided into test group and control group, and test group was coated with a TiO2/ZrO2 complex film on the surface by plasma spraying technology. The microstructure of the coating was analyzed by energy-dispersive spectrometry and scanning electron microscope. The metal-porcelain bond samples were made from both groups and Titankeramik porcelain which were used for metal-porcelain bond strength measurement. The extraction liquid of the coating was obtained and cell relative growth rate(RGR) was calculated through methyl thiazolyl tetrazolium assay by which the cytotoxicity was graded. Results The TiO/ZrO2 coating were well bonded with titanium and no obvious fracture was observed. The metal-porcelain bonding strength of test group were higher than control group significantly (P<0.05). The toxicity gradation of all groups was 0-1, RGR of all groups were almost the same and increased with culture time. Conclusion The results indicate that the TiO2/ZrO2 coating are well bonded with titanium which can improve the metal-porcelain bond strength of titanium and is compatible with the tested cells.

关键词

纯钛/等离子喷涂/涂层/结合强度/细胞毒性

Key words

titanium/plasma spraying/coating/bonding strength/cytotoxicity

分类

医药卫生

引用本文复制引用

司家文,万浩元,胡启凡,孙惠强..纯钛表面氧化钛和氧化锆涂层的结构性能及细胞毒性[J].国际口腔医学杂志,2011,(5):531-534,538,5.

基金项目

山东省自然科学基金资助项目(ZR2010HM035) (ZR2010HM035)

2008年度国家大学生创新性实验计划基金资助项目(081042224) (081042224)

国际口腔医学杂志

OACSTPCD

1673-5749

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