临床肝胆病杂志2011，Vol.27Issue(10)：1066-1068,1080,4.
187例自身免疫性肝病的临床特点分析
Clinical analysis of 187 patients with autoimmune liver diseases
高敏照 1刘玉兰1
作者信息
- 1. 北京大学人民医院消化科,北京100044
- 折叠
摘要
Abstract
Objective To analyze the clinical, biochemical and immunological characteristics of autoimmune liver disease(AILD). Meth ods The clinical, biochemical and immunological features of 187 patients with AILD were analyzed. Results AILD mainly affects 40 years old and older female patients. The clinical features are not typical. AIH is characterized by high y - globulin, alanine aminotransferase (ALT) and immunoglobulin G,but PBC is characterized by high alkaline phosphatase (ALP) , y - glutamy transpeptidase(GGT) and im-munoglobubin M. AILD patients will combine with one or multiple CTD, SS is common, more than 30% . 88% of patients with AILD pres ented significant liters of antinuclear antibody( ANA), and the positive rate of AMA, AMA - M2 was 96.4% and 94.4% in PBC patients, respectively. AIH patients mainly treated with corticosteroid, and 46 receive UDCA monotherapy or a combination of UDCA and corticoste roid or immunosuppressive agents. Conclusion The patients with autoimmune liver diseases could be diagnosed by biochemical, immuno logical features and detection of autoantibodies. UDCA is effective in patients with AIH.关键词
肝炎,自身免疫性/肝硬化,胆汁性Key words
hepatitis, autoimmune/ liver cirrhosis, biliary分类
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高敏照,刘玉兰..187例自身免疫性肝病的临床特点分析[J].临床肝胆病杂志,2011,27(10):1066-1068,1080,4.
