广西医科大学学报2011，Vol.28Issue(4)：493-495,3.
星点设计-效应面法优选两面针活性成分的提取工艺
SELECTION ON THE OPTIMAL EXTRACTION OF ZANTHOXYLUM NITIDUM(ROXB.) DC BY CENTRAL COMPOSITE DESIGN-RESPONSE SURFACE METHODOLOGY
摘要
Abstract
Objective:To optimize the extracting technology of active ingredients. Methods:The main influencing factors of extraction effect included the quantity of chloroform and extraction time and the extraction conditions were evaluated by the contents of nitidine chloride, ethoxychelerythrine and L-sesamin. The optimal extraction of active ingredients was selected by central composite design-response surface methodology. Results:The optimal conditions consisted of extraction three times, 120 min each time with sixty fold of chloroform. Conclusion:It is simple,convenient and high predictive to optimize the extraction craft of active ingredients by central composite design-response surface methodology.关键词
两面针/星点设计-效应面法/提取工艺Key words
zanthoxylum nitidum(Roxb. ) DC/ central composite design/ response surface methodology extraction technology分类
医药卫生引用本文复制引用
刘华钢,叶月华,冯看..星点设计-效应面法优选两面针活性成分的提取工艺[J].广西医科大学学报,2011,28(4):493-495,3.基金项目
国家自然科学基金资助项目(No.30760302) （No.30760302）
