天然产物研究与开发2011，Vol.23Issue(5)：801-804,4.
海洋真菌Xylaria sp.SOF11中细胞松弛素类化合物的研究
Cytochalasins from Marine-derived Fungus Xylaria sp.SOF11
摘要
Abstract
Three cytochalasins were obtained from the fermentation broth of the marine-derived fungus Xylaria sp. SOF11,which was isolated from marine sediment collected from the South China Sea. On the basis of 1H, 13C and 2D NMR spectral data,these compounds 1-3 were identified as 19,20-epoxycytochalasin Q (1) ,18-deoxy-19,20-epoxycy-tochalasin Q ( 2 ) and 19,20-epoxycytochalasin C (3). Compounds 1 -3 showed weak cytotoxicities against two tumor cell lines MCF-7 and NCI-H460 in a MTT assay.关键词
海洋真菌/炭角菌属/次级代谢产物/细胞松弛素Key words
marine-derived fungus/Xylaria sp. SOF11/secondary metabolite/cytochalasin分类
生物科学引用本文复制引用
陈子明,汪中文,黄洪波,陈玉婵,章卫民,张长生,鞠建华..海洋真菌Xylaria sp.SOF11中细胞松弛素类化合物的研究[J].天然产物研究与开发,2011,23(5):801-804,4.基金项目
中国科学院知识创新工程重要方向项目(KSCX2-YWG-065,KZCX2-YW-JC202,KZCX2-EW-G-12) （KSCX2-YWG-065,KZCX2-YW-JC202,KZCX2-EW-G-12）
广东省科技计划项目(2010B030600010) （2010B030600010）
中国科学院南海海洋所领域前沿项目(LYQY200805) （LYQY200805）
