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根皮素异烟酰基腙的合成、表征及抗氧化活性研究

李静 余燕影 曹树稳

天然产物研究与开发2011,Vol.23Issue(5):824-827,4.
天然产物研究与开发2011,Vol.23Issue(5):824-827,4.

根皮素异烟酰基腙的合成、表征及抗氧化活性研究

Synthesis, Characterization, and Antioxidant Activity of Phloretin Isonicotinyl Hydrazone

李静 1余燕影 2曹树稳1

作者信息

  • 1. 食品科学与技术国家重点实验室南昌大学,南昌330047
  • 2. 南昌大学化学系,南昌330031
  • 折叠

摘要

Abstract

To improve the biological activity of phloretin,a novel hydrazone was synthesis with phloretin and isoniazid, and the target compound was characterized by UV.IR.1H NMR,13C NMR and elemental analysis,respectively. Reducing power,DPPH and ABTS radical scavenging assays were carried out to evaluate the antioxidant and free radical scavenging abilities of phloretin and its hydrazone. The results showed that the antioxidant and free radical scavenging abilities of hydrazone was stronger than phloretin.

关键词

/根皮素/异烟肼/合成/抗氧化

Key words

hydrazone/phloretin/isoniazid/synthesis/antioxidant activity

分类

医药卫生

引用本文复制引用

李静,余燕影,曹树稳..根皮素异烟酰基腙的合成、表征及抗氧化活性研究[J].天然产物研究与开发,2011,23(5):824-827,4.

基金项目

国家自然科学基金项目(20962014) (20962014)

天然产物研究与开发

OA北大核心CSCDCSTPCD

1001-6880

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