天然产物研究与开发2011，Vol.23Issue(5)：853-856,930,5.
白皮锦鸡儿黄酮醇类化合物及其抗菌和抗氧化活性
Flavonol Derivatives from Caragana leucophloea and Their Antimicrobial and Antioxidant Activities
摘要
Abstract
Three flavonol derrvativea have been isolated from the aerial parts of Caragana leucophloea Pojark.( Leguminosae).By means of physicochemical and 8pectrometric analysis,they were identified as 3-O-methylkaempferol ( 1),3-O-methylquercetin (2),and quercetin (3).Among them,l exhibited the strongest antibacterial activity with its median inhibitory concentration (IC50 ),ralues on Escherichia coli and Ralstonia solanacearum as 9.00 μg/mL and 7.42 μg/mL,respectively,and minimum inhibitory concentration ( MIC) values on tbese two bacteria equally as 12.5 μg/mL.Either 2 or 3 showed stronger antioxidant activity than 1.The IC50 values of 2 and 3 on DPPH reduction were 14.39 μg/mL and 13.64 μg/mL,respectively,and those on β-carotene-linoleic acid oxidation were 10.26 μg/mL and 9.87 μg/mL,respectively.These flavonol derivatives were isolated from this plant species for the first time.<英文关键词>=Key words:Leguminosae ; Caragana leucophloea ; flavonol erivatives ; antimicrobial activity ; antioxidant activity关键词
豆科/白皮锦鸡儿/黄酮醇类化合物/抗菌活性/抗氧化活性Key words
Leguminosae/ Caragana leucophloea/ flavonol derivatives/antimicrobial activity/ antioxidant activity分类
农业科技引用本文复制引用
高海峰,郑兵兵,王蓟花,单体江,赵思峰,周立刚..白皮锦鸡儿黄酮醇类化合物及其抗菌和抗氧化活性[J].天然产物研究与开发,2011,23(5):853-856,930,5.基金项目
Foundation Item:This work was co-financed by the 8rants from the HiTech R&D Program of China (2011AA10A202),and the Special Fund for Agro-Selentific Research in the Public Interest of China (nyhyzx07-022 annd 200903052). （2011AA10A202）
