昆明医学院学报2011，Vol.32Issue(7)：120-123,4.
大剂量盐酸氨溴索防治新生儿呼吸窘迫综合征的临床观察
Clinical Observation on Large Dose of Ambroxol Hydrochloride in Prevention and Treatment of Neonatal Respiratory Distress Syndrome
梁静玲 1曹虹 1周锦妍 1李克蓉1
作者信息
- 1. 昆明市延安医院儿科,云南昆明650051
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy and safety of ambroxol hydrochloride in preventing and treating neonatal respiratory distress syndrome (NRDS). Methods 91 premature infants were divided into two groups randomly. 45 premature infants in control group were preformed with combined therapy. On this basis, 46 cases in treatment group were given ambroxol hydrochloride, 7.5 mg/kgt intervenous drop infusion, once every six hours, the course of treatment was 7 days. Results The incidence of NRDS in the treatment group was lower than that in the control group (15% vs 40% ). The respiratory distress relief time, oxygen time and the lengths of hospitalization in the treatment group were shorter than those in the control group C(77.6±9.1) hvs (83.3 ±10.5) h; (69.2±7.6) h vs (74.2 ±8.9) h; (12.5 ±2.9) d vs (14.7 ±3.4) d, respectively] , there was a significant difference (P<0.0l). Conclusion Ambroxol hydrochloride has significant clinical effects in prevention and treatment of NRDS, and deserves to generalize in clinic.关键词
新生儿/早产儿/呼吸窘迫综合征/盐酸氨溴索Key words
Neoaate/Premature infant/ Respiratory distress syndrome/ Ambroxol hydrochloride分类
临床医学引用本文复制引用
梁静玲,曹虹,周锦妍,李克蓉..大剂量盐酸氨溴索防治新生儿呼吸窘迫综合征的临床观察[J].昆明医学院学报,2011,32(7):120-123,4.
