中国组织工程研究与临床康复2011，Vol.15Issue(41)：7734-7737,4.DOI:10.3969/j.issn.1673-8225.2011.41.033
SPF级Balb/c小鼠脏器质量、脏器系数、血常规、血生化指标的测定与比较
Measurement and comparisons of organ weight, organ coefficient, hematological parameters and hematological biochemical parameters of specific pathogen free Balb/c mice
摘要
Abstract
BACKGROUND: Measuring important basic data of experimental animals is the important basis for standardization and management of experimental animals. OBJECTIVE: To measure and compare organ weight, organ coefficient, hematological parameters and hematological biochemical parameters of specific pathogen free (SPF) Balb/c mice. METHODS: A total of 240 Balb/c mice were fed for 1 week and then organ weights, organ coefficient, hematological parameters and hematological biochemical parameters were measured. RESULTS AND CONCLUSION: There were significant differences in weights of the heart, lung, spleen, double kidneys, and bladder between female and male Balb/c mice (P < 0.01 or P < 0.05). There were significant differences in organ coefficient of lung, spleen, double kidneys and bladder between female and male Balb/c mice (P < 0.01 or P < 0.05). There were significant differences in leukocyte, monocytes, basophils, monocytes (%), eosinophils, basophils (%), erythrocyte, hemoglobin, mean corpuscular hemoglobin concentration, and red blood cell distribution width between female and male Balb/c mice (P < 0.01 or P < 0.05). There were significant differences in total protein, albumin, A/G, glucose, urea nitrogen, creatinine, uric acid, triglycerides, total cholesterol, low density lipoprotein, high density lipoprotein, iron, and phosphorus between female and male Balb/c mice(P < 0.01 or P < 0.05). These results suggest that gender has influences on organ weight, organ coefficient, hematological parameters and hematological biochemical parameters of SPF Balb/c mice.关键词
小鼠/脏器质量/血常规/血生化/性别分类
基础医学引用本文复制引用
张修彦,詹纯列,肖育华,唐咸国..SPF级Balb/c小鼠脏器质量、脏器系数、血常规、血生化指标的测定与比较[J].中国组织工程研究与临床康复,2011,15(41):7734-7737,4.基金项目
广东省科学技术厅科技基础条件建设项目(2008A060202016). （2008A060202016）
