中国组织工程研究与临床康复2011，Vol.15Issue(41)：7747-7750,4.DOI:10.3969/j.issn.1673-8225.2011.41.037
组织工程化软骨修复关节软骨缺损
Tissue-engineered cartilage for treatment of articular cartilage defects
摘要
Abstract
BACKGROUND: At present, the methods for treatment of articular cartilage defects have obvious shortcomings. Tissue-engineered cartilage for repair of articular cartilage defects provides a novel method to treat cartilage defects with minimal invasion. OBJECTIVE: To summarize the research progress in tissue-engineered cartilage for repair of articular cartilage degects. METHODS: A computer-based retrieval was performed by the first author in the Wanfang data (2000/2010)and Pubmed database (2000/2010) using the key words “articular cartilage defects, tissue-engineered cartilage” in English and Chinese. The development and construction of tissue-engineered cartilage were summarized. A total of 666 manuscripts were searched. According to inclusion and exclusion criteria, 23 manuscripts were included in the final analysis. RESULTS AND CONCLUSION: With increasing development of cell scaffold material and tissue construction technique, tissue-engineered cartilage of active cells and scaffold material provides a novel therapeutic method for treatment of articular cartilage defects with minimal invasion, so tissue-engineered cartilage for treatment of cartilage defects is completely feasible, and C-GP gel has good compatibility with seeded cells and can be used as the ideal scaffold for tissue-engineered cartilage. But preparation and selection of cell scaffold remains a difficult problem for tissue-engineered cartilage.关键词
组织工程软骨/关节软骨/缺损/支架/软组织构建分类
基础医学引用本文复制引用
许荣耀,张寿..组织工程化软骨修复关节软骨缺损[J].中国组织工程研究与临床康复,2011,15(41):7747-7750,4.基金项目
课题受海口市重点基金项目(2010-168) 资助. （2010-168）
