中国组织工程研究与临床康复2011,Vol.15Issue(42):7877-7880,4.DOI:10.3969/j.issn.1673-8225.2011.42.021
壳聚糖/介孔生物活性玻璃多孔膜的制备和表征
Fabrication and characterization of chitosan/mesoporous bioactive glasses porous films
摘要
Abstract
BACKGROUND: Chitosan (CS) and mesoporo us bioactive glasses (MBG) have some good properties, such as bio com pati bil ity and hemostasis, but the hemostatic effect of CS is limited and it is inconvenient to use the MB<3 directly. OBJECTIVE: To prepare C S/MBG porous filmsMETHODS: CS and MBG porous film was prepared through a freeze drying process. The prepared porous films were characterized by us ing Fourier transform infrared spectres copy, scanning electron microscope and X-ray diffraction. In addtion, water adsorption, swelling ratio, the porosity and the mechanical property of the porous films were also studied. RESLUTS AND CONCLUSION: CS/MBG could be blended homogeneously via the lyophilization. The hole of the porous films was relatively uniform. The porous films showed good water adsorption character, which could be modulated by varying the weight ratio of CS and MBG. The prepared porous films had a higher porosity. The composite films can be potentially applied as a wound dressing material.关键词
介孔生物玻璃/壳聚糖/冷冻干燥/多孔膜/止血分类
医药卫生引用本文复制引用
贾天保,陈建勇,冯新星,常江..壳聚糖/介孔生物活性玻璃多孔膜的制备和表征[J].中国组织工程研究与临床康复,2011,15(42):7877-7880,4.基金项目
国家自然科学基金项(50973096,50903073,31070867) (50973096,50903073,31070867)
浙江省科技厅公益项目(2010C31038). (2010C31038)