中国康复理论与实践2011，Vol.17Issue(7)：654-656,3.
康复训练对A型肉毒毒素治疗痉挛型脑瘫长期疗效的影响
Effect of Rehabilitation on Long-term Efficacy of Botulinum Toxin Type A on Spastic Cerebral Palsy
刘建军 1纪树荣 1吴卫红 1张雁 1曾凡勇 1李南玲1
作者信息
摘要
Abstract
Objective To investigate the long-term efficacy of Botulinum toxin type A (BTX-A) on spasticity in cerebral palsy, and the effect of rehabilitation on it. Methods 230 children with spastic cerebral palsy were treated with BTX-A block. The dose of BTX-A was identified with the weight of the children and the Modified Ashworth Scale (MAS). They were divided into group A who exercised more than 2 h/d, and group B who exercised less than 2 h/d or not. They were assessed with Gross Motor Function Measure (GMFM) 1 year after treatment. Results There was no significant difference between group A and B with ages, weight, MAS, GMFM before block (P>0.05), nor with BTX-A effect time (P>0.05). The GMFM improved significantly in both group A and B 1 year after block (P<0.05), and it improved more in group A than group B (P<0.0\). Conclusion The long-term efficacy of BTX-A block is positive. The rehabilitation training after block can help children to improve their gross motor function.关键词
脑性瘫痪；痉挛；A型肉毒毒素；长期疗效；神经阻滞；康复Key words
cerebral palsy/ spasticity/ Botulinum toxin type A/ long-term efficacy/ nerve block/ rehabilitation分类
医药卫生引用本文复制引用
刘建军,纪树荣,吴卫红,张雁,曾凡勇,李南玲..康复训练对A型肉毒毒素治疗痉挛型脑瘫长期疗效的影响[J].中国康复理论与实践,2011,17(7):654-656,3.
