中国临床药理学杂志2011，Vol.27Issue(7)：508-516,9.
Mohnarin2009年度报告：青壮年(14-65岁)来源菌株耐药监测
Mohnarin 2009 annual report:Bacterial resistance surveillance in patients between 14 and 65 years old
刘根焰 1童明庆 1梅亚宁 1顾兵 1赵旺胜 1潘世扬1
作者信息
- 1. 南京医科大学第一附属医院医学检验科，南京210029
- 折叠
摘要
Abstract
Objective To understand pathogenic bacteria distribution and drug resistance of the bacteria isolated from Chinese young and mid-aged patients (14-65 years). Methods All antimicrobial susceptibility test data of 114 member hospitals from 1 Jan. To 31 Dec. In the year 2009 were collected according to the Mohnarin surveillance program and CLSI 2009 rules. All the data came from young and mid - aged patients (14-65 years) were analyzed by WHONET 5.5 software. Results A total data of 208208 isolates were submitted by 114 member hospitals in the year 2009. Isolates of 82115 (39.44% ) were from young and mid - aged adults. Gram - negative bacteria accounted for 70.04% , of which E. Coli 14696 (17.90% ) , KkbsieUa pneunwniae 8517 (10.37% ) , Pseudomonas aeruginosa 7903 (9.62% ) and Acinetobacter baumannii 7309 (8.90%). Gram - positive bacteria accounted for 29.96%, including Staphylococcus aureus 7550 ( 9.19%), Staphylococcus epidermidis 4068 (4. 95% ) , Enterococcusfaecalis 3099 (3. 77% ) and Enterococcus faedum 2590 (3.15% ). With gram - positive bacteria, drug susceptibility data showed that linezolid and vancomycin was still 100% sensitive to Staphylococci, most important is teicoplanin - resistant Staphylococcus aureus (0. 8% ) and vancomycin - resistant Enterococcus faedum (2. 6% ) were emergented. With gram - negative isolates, ESBLs producing Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis were 62. 1% , 42. 4% and 27. 5% respectively. To be worth mentioned is a few bacteria of Enter-obacteriaceae has gotten resistance to carbopenems. Non - fermenting bacteria still keep high resistant to various antimicrobial agents except polymyxin B , polymyxin C and carbopenems, for which they all keep more than 70% sensitivity excluding Acinetobacter baumannii with less than 50% sensitivity to carbopenem. Most of fastidious bacteria keep high sensitivity to kinds of antibiotics but seldom isolated from young and mid - aged patients. Conclusion Strains isolated from Chinese young and mid - aged patients were mainly gram negative bacteria,which became more resistant to antimicrobial agents than ever. Strengthen surveillance of bacterial resistance and promote the rational use of antibiotics is very important关键词
细菌；耐药性；青壮年(14-65岁)感染Key words
bacterial/drugs resistance/infection of young and mid - aged patients (14-65 years)分类
医药卫生引用本文复制引用
刘根焰,童明庆,梅亚宁,顾兵,赵旺胜,潘世扬..Mohnarin2009年度报告：青壮年(14-65岁)来源菌株耐药监测[J].中国临床药理学杂志,2011,27(7):508-516,9.
