中国临床药理学杂志2011，Vol.27Issue(7)：524-532,9.
Mohnarin2009年度报告：华北地区细菌耐药监测
Mohnarin 2009 annual report: Bacterial distribution and resistance surveillance in north China
艾效曼 1陶凤蓉 1许宏涛 1陈东科 1张秀珍 1胡云建1
作者信息
- 1. 卫生部北京医院医学检验室，北京100730
- 折叠
摘要
Abstract
Objective To investigate the drug resistance of clinical isolates from hospitals in north China in 2009. Methods Bacterial susceptibility testing was carried out according to an agreed protocol and standard. The results were analyzed by WH0NET5.4. Results A total of 48085 clinical isolates were collected from January to December 2009, of which Gram negative microorganisms and gram positive cocci accounted for 68.72% and 31. 28% , respectively. Methicillin resistant strains in S. Aureus( MRSA) and MRSCON accounted for an average 32. 8% and 68.4% , respectively. NoS. Aureus isolates were found resistant to vanco-mycin, teicoplanin and linezolin, but there are 35 isolates in other Stapthacocci spp. Non - susceptibility to teicoplanin. There are 0. 6% , 0. 1% of E.faecalis and 6.5% , 3. 8% of E. Faecium strains resistant to vancomycin and teicoplan, respectively. In the 260 strains of S. Pneumoniae, 70.7% were identified as penicillin resistant S. Pneumo-nia( PRSP) respectively if used the standard of in - cerebrospinal fluid (CSF) , if used the non - in CSF, 2. 6% were identified as penicillin - resistant Streptococcus pneumoniae. About 59.1% of E. Coli and 37. 8% of Klebsiella pneumonia were the strains producing ESBLs. There were 34. 5% of H. Influenza isolates resistances to AMP. Isolates of Enterobacteriaceae were still highly sensitive to imipenem and meropen-em, the average resistance rates was less than 2%. Conclusion Bacterial resistance was still on the rise in north China , and it was very important to reasonable application antibiotics and prevents the dissemination and outbreak of pan - resistant bacteria.关键词
细菌耐药监测；抗菌药物Key words
bacterial resistance surveillance/ antibacterial agents分类
医药卫生引用本文复制引用
艾效曼,陶凤蓉,许宏涛,陈东科,张秀珍,胡云建..Mohnarin2009年度报告：华北地区细菌耐药监测[J].中国临床药理学杂志,2011,27(7):524-532,9.
