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肝气郁结模型大鼠正电子发射脑功能成像研究

刘子旺 赵海滨 张秀静 单保慈 刘华 贺立娟

中国康复理论与实践2011,Vol.17Issue(9):837-839,3.
中国康复理论与实践2011,Vol.17Issue(9):837-839,3.

肝气郁结模型大鼠正电子发射脑功能成像研究

Findings in Positron Emission Tomography of Brain in Rats with Syndrome of Stagnation of Liver-Qi

刘子旺 1赵海滨 1张秀静 1单保慈 2刘华 2贺立娟3

作者信息

  • 1. 北京中医药大学第三附属医院,北京市100029
  • 2. 中国科学院高能物理研究所,北京市100039
  • 3. 北京中医药大学东方医院,北京市100078
  • 折叠

摘要

Abstract

Objective To explore the characteristics of brain function in rats with Stagnation of Liver-qi Syndrome. Methods Model of Stagnation of Liver-qi was made with chronic stress combined with isolated raising in 10 normal Wistar rats. They were scanned with positron emission tomography (PET) before and after modeling. Data analysis was carried out using SPM (statistical parametric mapping 2) in MATLAB software. Results After modeling, the glucose metabolism decreased (P<0.001) in left frontal lobe, parietal lobe, hypothalamus; bilateral posterior cingulate; right anterior cingulate, while the glucose metabolism increased (P<0.001) in left parahippocampal gyrus, insu-la, temporal lobe, frontal lobe; right basal ganglia, thalamus. Conclusion The function of some cerebral areas can be changed undergoing Stagnation of Liver-qi Syndrome.

关键词

肝气郁结证/大鼠/正电子发射计算机断层显像/脑功能

Key words

Stagnation of Liver-qi Syndrome/ rats/ positron emission tomography/ cerebral function

分类

医药卫生

引用本文复制引用

刘子旺,赵海滨,张秀静,单保慈,刘华,贺立娟..肝气郁结模型大鼠正电子发射脑功能成像研究[J].中国康复理论与实践,2011,17(9):837-839,3.

基金项目

1.高等学校博士学科点专项科研基金(No.200800261017) (No.200800261017)

2.首都医学发展科研基金(No.SF-2007-Ⅲ-06). (No.SF-2007-Ⅲ-06)

中国康复理论与实践

OA北大核心CSCDCSTPCD

1006-9771

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