中国康复理论与实践2011,Vol.17Issue(9):837-839,3.
肝气郁结模型大鼠正电子发射脑功能成像研究
Findings in Positron Emission Tomography of Brain in Rats with Syndrome of Stagnation of Liver-Qi
摘要
Abstract
Objective To explore the characteristics of brain function in rats with Stagnation of Liver-qi Syndrome. Methods Model of Stagnation of Liver-qi was made with chronic stress combined with isolated raising in 10 normal Wistar rats. They were scanned with positron emission tomography (PET) before and after modeling. Data analysis was carried out using SPM (statistical parametric mapping 2) in MATLAB software. Results After modeling, the glucose metabolism decreased (P<0.001) in left frontal lobe, parietal lobe, hypothalamus; bilateral posterior cingulate; right anterior cingulate, while the glucose metabolism increased (P<0.001) in left parahippocampal gyrus, insu-la, temporal lobe, frontal lobe; right basal ganglia, thalamus. Conclusion The function of some cerebral areas can be changed undergoing Stagnation of Liver-qi Syndrome.关键词
肝气郁结证/大鼠/正电子发射计算机断层显像/脑功能Key words
Stagnation of Liver-qi Syndrome/ rats/ positron emission tomography/ cerebral function分类
医药卫生引用本文复制引用
刘子旺,赵海滨,张秀静,单保慈,刘华,贺立娟..肝气郁结模型大鼠正电子发射脑功能成像研究[J].中国康复理论与实践,2011,17(9):837-839,3.基金项目
1.高等学校博士学科点专项科研基金(No.200800261017) (No.200800261017)
2.首都医学发展科研基金(No.SF-2007-Ⅲ-06). (No.SF-2007-Ⅲ-06)