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一氧化碳中毒迟发性脑病高压氧治疗剂量与疗效

张红霞 刘亚玲 于秋红 薛连璧

中国康复理论与实践2011,Vol.17Issue(9):868-871,4.
中国康复理论与实践2011,Vol.17Issue(9):868-871,4.

一氧化碳中毒迟发性脑病高压氧治疗剂量与疗效

Efficacy of Different Doses of Hyperbaric Oxygen Therapy on Delayed Encephalopathy after Carbon Monoxide Poisoning

张红霞 1刘亚玲 1于秋红 1薛连璧1

作者信息

  • 1. 首都医科大学附属北京天坛医院高压氧科,北京市100050
  • 折叠

摘要

Abstract

Objective To evaluate the efficacy of two doses of hyperbaric oxygen therapy (HBOT) on delayed encephalopathy after carbon monoxide poisoning (DEACMP). Methods 68 patients with DEACMP were divided into two groups, the 30 sessions of HBOT group (30-HBOT group) and the 60 sessions of HBOT group (60-HBOT group), who were given HBOT 30 and 60 times respectively. All patients were assessed with Mini-Mental State Examination (MMSE) and fluid attenuated inversion recovery (Flair) magnetic resonance imaging of brain immediately before, 35 d and 70 d after HBOT. Results The MMSE score was significantly higher in 60-HBOT group than in 30-HBOT group 70 d after HBOT (P<0.01). All of patients showed diffuse and confluent hyper-intensity over the bilateral periventricular white matter and centrum semiovale on conventional T2WI and Flair, which improved. Conclusion HBOT is effective on DEACMP, especially with 60 times.

关键词

高压氧治疗/一氧化碳中毒迟发性脑病/简易智能精神状态检查量表/核磁共振成像

Key words

hyperbaric oxygen therapy/ delayed encephalopathy after carbon monoxide poisoning/ Mini-Mental State Examination/ magnetic resonance imaging

分类

医药卫生

引用本文复制引用

张红霞,刘亚玲,于秋红,薛连璧..一氧化碳中毒迟发性脑病高压氧治疗剂量与疗效[J].中国康复理论与实践,2011,17(9):868-871,4.

基金项目

北京市优秀人才基金2002. ()

中国康复理论与实践

OA北大核心CSCDCSTPCD

1006-9771

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