中国普通外科杂志2011，Vol.20Issue(10)：1029-1032,4.
结直肠癌肝转移复发再次肝切除术的疗效与预后分析
Effectiveness and prognosis of repeat liver resection for recurrent liver metastases from colorectal cancer
周进学 1曹新广 2陈小兵 3韩风 1丁月超 1万百顺1
作者信息
- 1. 河南省肿瘤医院(郑州大学附属肿瘤医院)肝胆外科,河南郑州450008
- 2. 河南省肿瘤医院(郑州大学附属肿瘤医院)腔镜中心,河南郑州450008
- 3. 河南省肿瘤医院(郑州大学附属肿瘤医院)内科,河南郑州450008
- 折叠
摘要
Abstract
Objective To determine the value of repeat liver resection for recurrent colorectal liver metastases. Methods The clinical data of 43 patients with recurrent colorectal liver metastases undergoing repeat liver resection and 67 patients with recurrent colorectal liver metastases undergoing systemic chemotherapy were retrospectively analyzed. Results The 1-, 3- and 5-year survival rate of the repeat liver resection group was 83. 7%, 51. 1% and 27. 9% , respectively, and of the chemotherapy group was 65.1% , 20. 6% and 3. 0% , respectively (P < 0.05 or P < 0. 01) . In the repeat liver resection group , no operative death occurred and the incidence rate of complications was 32. 6%. Univariate analysis suggested that the number of recurrent liver metastasis, condition of the surgical margin, CEA level, tumor size and degree of tumor differentiation were related to the prognosis. Multivariate regression analysis revealed that only the number of recurrent liver metastasis and tumor size were independent risk factors for predicting the prognosis. Conclusions Repeat liver resection is a safe treatment for patients with recurrent colorectal liver metastases, and is especially suitable for those with a low hepatic tumor load (tumor size less than 5 cm and metastases number fewer than 3) .Repeat hepatectomy can prolong the survival of selected patients with recurrent colorectal liver metastases.关键词
结直肠肿瘤/肿瘤转移/肝肿瘤,继发性/再次肝切除术/预后Key words
Colorectal Neoplasms/ Neoplasm Metastasis/ liver Neoplasms , Secondary/ Repeat Hepatectomy/ Prognosis分类
医药卫生引用本文复制引用
周进学,曹新广,陈小兵,韩风,丁月超,万百顺..结直肠癌肝转移复发再次肝切除术的疗效与预后分析[J].中国普通外科杂志,2011,20(10):1029-1032,4.
